职称：副教授
学位：农学博士
专业：动物遗传育种与繁殖
办公室：综合楼实验楼 博士工作室
联系方式： weixuefeng.happy@163.com
教育经历
2013-2017 西北农林科技大学动物科技学院，农学博士
2010-2013云南农业大学动物科技学院，农学硕士
2006-2010湖州师范学院生命科学学院，理学学士
工作经历
2017.09- 至今 信阳师范学院 生命科学学院 讲师
教学情况
主讲课程：本科生课程《遗传学》、《实验动物学》、《生物技术制药》，研究生课程《表观遗传学》、《生物发展史》
研究领域
家畜肌肉组织发育和脂肪沉积的重要基因挖掘及分子调控机理研究，主要关注肌肉和脂肪相关功能基因、非编码RNA miRNA、circRNA功能、互作及调控机制。
主持科研项目
主持国家自然科学基金青年项目，信阳师范学院高层次人才科研启动基金项目共2项，参与中原科技创新领军人才项目1项；
1. 国家自然科学基金青年项目，“牛CircMYBPC1调控肌原代细胞增殖、分化的分子机制解析”，2019.01-2021.12，27万，在研，主持。
2. 信阳师范学院高层次人才科研启动基金项目，“长链非编码RNA调控牛肌细胞增殖分化的分子机制研究”，在研，主持。
发表论文
1、Xuefeng Wei, Hui Li, Bowen Zhang, ... & Hong Chen*. miR-378a-3p promotes differentiation and inhibits proliferation of myoblasts by targeting HDAC4 in skeletal muscle development. RNA Biology, 2016, 13(12): 1300-1309.
2、Xuefeng Wei, Hui Li, Jiameng Yang, ... & Hong Chen*. Circular RNA profiling reveals an abundant circLMO7 that regulates myoblasts differentiation and survival by sponging miR-378a-3p. Cell Death & Disease. 2017, 8(10): e3153.
3、Xuefeng Wei, Hui Li, Guangwei Zhao, ... & Hong Chen*. ΔFosB regulates rosiglitazone-induced milk fat synthesis and cell survival. Journal of cellular physiology, 2017, 11.20. DOI:10.1002/jcp.26218.
4、Hui Li#, Xuefeng Wei#, Jiameng Yang, ... & Hong Chen*. circFGFR4 Promotes Differentiation of Myoblasts via Binding miR-107 to Relieve Its Inhibition of Wnt3a. Molecular Therapy-Nucleic Acids, 2018, 11: 272-283. (#，co-first)
5、Hui Li#, Xuefeng Wei#, Jiameng Yang, ... & Hong Chen*. Development transcriptome profiling of bovine muscle tissue reveals an aboundant GosB the regulates myoblasts proliferation and apoptosis. Oncotarget, 2017, 8(19):32083-32100.
6、Hui Li#, Jiameng Yang#, Xuefeng Wei#, Chengchuang Song, ... & Hong Chen*. CircFUT10 reduces proliferation and facilitates differentiation of myoblasts by sponging miR-133a. Journal of cellular physiology, 2018, 233(6): 4643-4651.
7、Xuefeng Wei, Shuang Han, Shuzhe Wang ... Yun Ma. ANGPTL8 regulates adipocytes differentiation and adipogenesis in bovine. Gene, 2019, 707: 93-99.
8、Xuefeng Wei, Yunchang Zhu, Jie Du ... Yun Ma. Analysis of ANGPTL8 promoter activity and screening of related transcription factors in bovine. Gene, 2021, 784: 145594.
9、Mengjie Chen,# Xuefeng Wei,# Mingming Song, ... & Hui Li*. Circular RNA circMYBPC1 promotes skeletal muscle differentiation by targeting MyHC. Molecular Therapy-Nucleic Acids, 2021, 24: 352-368. (#，co-first)
10、 Bowen Zhang, Hanfang Cai, Xuefeng Wei, Jiajie Sun, ... & Hong Chen. MiR-30-5p Regulates Muscle Differentiation and Alternative Splicing of Muscle-Related Genes by Targeting MBNL. International Journal of Molecular Sciences. 2016, 17(2), 182.
11、 Mingxun Li, Xiaomei Sun, Yang Zhou, Xuefeng Wei, ... & Hong Chen. Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism. Journal of Functional Foods 2015, 18, 492-500.
